Cargando…

PI3K‐α/mTOR/BRD4 inhibitor alone or in combination with other anti‐virals blocks replication of SARS‐CoV‐2 and its variants of concern including Delta and Omicron

Detalles Bibliográficos
Autores principales:	Acharya, Arpan, Pathania, Anup S., Pandey, Kabita, Thurman, Michellie, Vann, Kendra R., Kutateladze, Tatiana G., Challagundala, Kishore B., Durden, Donald L., Byrareddy, Siddappa N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Letter to Editor
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989379/ https://www.ncbi.nlm.nih.gov/pubmed/35390226 http://dx.doi.org/10.1002/ctm2.806

Ejemplares similares

Binding of the SARS-CoV-2 envelope E protein to human BRD4 is essential for infection
por: Vann, Kendra R., et al.
Publicado: (2022)

Discovery and Evaluation of Entry Inhibitors for SARS-CoV-2 and Its Emerging Variants
por: Acharya, Arpan, et al.
Publicado: (2021)

Biomarkers of Activation and Inflammation to Track Disparity in Chronological and Physiological Age of People Living With HIV on Combination Antiretroviral Therapy
por: Thurman, Michellie, et al.
Publicado: (2020)

Mental Health Issues During and After COVID-19 Vaccine Era
por: Pandey, Kabita, et al.
Publicado: (2021)

Characterization of multiple interactions between the envelope E protein of SARS-CoV-2 and human BRD4
por: Zandian, Mohamad, et al.
Publicado: (2022)

Diminished Peripheral CD29hi Cytotoxic CD4+ T Cells Are Associated With Deleterious Effects During SIV Infection
por: Olwenyi, Omalla A., et al.
Publicado: (2021)

Combining antiviral drugs with BET inhibitors is beneficial in combatting SARS‐CoV‐2 infection
por: Acharya, Arpan, et al.
Publicado: (2022)

Proteomic landscape of astrocytes and pericytes infected with HIV/SARS-CoV-2 mono/co-infection, impacting on neurological complications
por: Acharya, Arpan, et al.
Publicado: (2023)

Chronic Morphine Administration Differentially Modulates Viral Reservoirs in a Simian Immunodeficiency Virus SIVmac251-Infected Rhesus Macaque Model
por: Acharya, Arpan, et al.
Publicado: (2021)

Systems biology analyses reveal enhanced chronic morphine distortion of gut-brain interrelationships in simian human immunodeficiency virus infected rhesus macaques
por: Olwenyi, Omalla A., et al.
Publicado: (2022)

The BTK/PI3K/BRD4 axis inhibitor SRX3262 overcomes Ibrutinib resistance in mantle cell lymphoma
por: Pal, Dhananjaya, et al.
Publicado: (2021)

Therapeutic implications of SARS-CoV-2 dysregulation of the gut-brain-lung axis
por: Johnson, Samuel D, et al.
Publicado: (2021)

Impact of Social Determinants of Health on the Emerging COVID-19 Pandemic in the United States
por: Singu, Sravani, et al.
Publicado: (2020)

Early treatment with anti-α(4)β(7) antibody facilitates increased gut macrophage maturity in SIV-infected rhesus macaques
por: Johnson, Samuel D., et al.
Publicado: (2022)

COVID-19 and Cancer Comorbidity: Therapeutic Opportunities and Challenges
por: Pathania, Anup S., et al.
Publicado: (2021)

Combinatorial inhibition of BTK, PI3K-AKT and BRD4-MYC as a strategy for treatment of mantle cell lymphoma
por: Vann, Kendra R., et al.
Publicado: (2022)

Peptide Nanoarray Scaffold Vaccine for SARS-COV-2 and Its Variants of Concerns
por: Zagorski, Karen, et al.
Publicado: (2022)

The 2022 outbreak and the pathobiology of the monkeypox virus
por: Kumar, Narendra, et al.
Publicado: (2022)

A commentary on “PI3K‐α/mTOR/BRD4 inhibitor alone or in combination with other anti‐virals blocks replication of SARS‐CoV‐2 and its variants of concern including Delta and Omicron”
por: Muthu, Sakthijothi, et al.
Publicado: (2022)

SARS-CoV-2 Infection Leads to Neurological Dysfunction
por: Acharya, Arpan, et al.
Publicado: (2020)

Design of thienopyranone-based BET inhibitors that bind multiple synthetic lethality targets
por: Vann, Kendra R., et al.
Publicado: (2020)

Modular nanoarray vaccine for SARS-CoV-2
por: Zagorski, Karen, et al.
Publicado: (2022)

Molecular Aspects of COVID-19 Differential Pathogenesis
por: Rothan, Hussin A., et al.
Publicado: (2020)

Therapeutic Potential of Cannabis: A Comprehensive Review of Current and Future Applications
por: Leinen, Zach J., et al.
Publicado: (2023)

Immunomodulatory LncRNA on antisense strand of ICAM-1 augments SARS-CoV-2 infection-associated airway mucoinflammatory phenotype
por: Devadoss, Dinesh, et al.
Publicado: (2022)

Long Term Delta-9-tetrahydrocannabinol Administration Inhibits Proinflammatory Responses in Minor Salivary Glands of Chronically Simian Immunodeficieny Virus Infected Rhesus Macaques
por: Alvarez, Xavier, et al.
Publicado: (2020)

Retinoic Acid Improves the Recovery of Replication-Competent Virus from Latent SIV Infected Cells
por: Olwenyi, Omalla A., et al.
Publicado: (2020)

miR-15a and miR-15b modulate natural killer and CD8(+)T-cell activation and anti-tumor immune response by targeting PD-L1 in neuroblastoma
por: Pathania, Anup S., et al.
Publicado: (2022)

Omicron SARS-CoV-2 variant: Unique features and their impact on pre-existing antibodies
por: Kannan, Saathvik R., et al.
Publicado: (2022)

Evolutionary analysis of the Delta and Delta Plus variants of the SARS-CoV-2 viruses
por: Kannan, Saathvik R., et al.
Publicado: (2021)

Inhibition of translation and immune responses by the virulence factor Nsp1 of SARS-CoV-2
por: Vann, Kendra R., et al.
Publicado: (2020)

Defining the Innate Immune Responses for SARS-CoV-2-Human Macrophage Interactions
por: Abdelmoaty, Mai M., et al.
Publicado: (2021)

Catching BETs by viruses
por: Zandian, Mohamad, et al.
Publicado: (2022)

ACE-2, TMPRSS2, and Neuropilin-1 Receptor Expression on Human Brain Astrocytes and Pericytes and SARS-CoV-2 Infection Kinetics
por: Malik, Johid Reza, et al.
Publicado: (2023)

Immune landscape of female reproductive tract and HIV susceptibility
por: Byrareddy, Siddappa N.
Publicado: (2021)

A triple action CDK4/6-PI3K-BET inhibitor with augmented cancer cell cytotoxicity
por: Burgoyne, Adam M., et al.
Publicado: (2020)

Protocol for Biochemical Analysis and Structure Determination of the ZZ Domain of the E3 Ubiquitin Ligase HERC2
por: Liu, Jiuyang, et al.
Publicado: (2020)

The slo-1 BK potassium channel interacts genetically with pmr-1 secretory pathway calcium ATPase during C. elegans embryonic cell migration
por: Thurman, Michellie, et al.
Publicado: (2021)

The BRD4–NUT Fusion Alone Drives Malignant Transformation of NUT Carcinoma
por: Durall, R. Taylor, et al.
Publicado: (2023)

Complex Mutation Pattern of Omicron BA.2: Evading Antibodies without Losing Receptor Interactions
por: Kannan, Saathvik R., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_2i0v3qkthti9vojagitt14vq86