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Nivolumab plus radiotherapy with or without temozolomide in newly diagnosed glioblastoma: Results from exploratory phase I cohorts of CheckMate 143

BACKGROUND: The phase 1 cohorts (1c+1d) of CheckMate 143 (NCT02017717) evaluated the safety/tolerability and efficacy of nivolumab plus radiotherapy (RT) ± temozolomide (TMZ) in newly diagnosed glioblastoma. METHODS: In total, 136 patients were enrolled. In part A (safety lead-in), 31 patients (n =...

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Detalles Bibliográficos
Autores principales:	Omuro, Antonio, Reardon, David A, Sampson, John H, Baehring, Joachim, Sahebjam, Solmaz, Cloughesy, Timothy F, Chalamandaris, Alexandros-Georgios, Potter, Von, Butowski, Nicholas, Lim, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Clinical Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989388/ https://www.ncbi.nlm.nih.gov/pubmed/35402913 http://dx.doi.org/10.1093/noajnl/vdac025

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