A novel immunopeptidomic-based pipeline for the generation of personalized oncolytic cancer vaccines

Besides the isolation and identification of major histocompatibility complex I-restricted peptides from the surface of cancer cells, one of the challenges is eliciting an effective antitumor CD8+ T-cell-mediated response as part of therapeutic cancer vaccine. Therefore, the establishment of a solid...

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Detalles Bibliográficos
Autores principales: Feola, Sara, Chiaro, Jacopo, Martins, Beatriz, Russo, Salvatore, Fusciello, Manlio, Ylösmäki, Erkko, Bonini, Chiara, Ruggiero, Eliana, Hamdan, Firas, Feodoroff, Michaela, Antignani, Gabriella, Viitala, Tapani, Pesonen, Sari, Grönholm, Mikaela, Branca, Rui MM, Lehtiö, Janne, Cerullo, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989416/
https://www.ncbi.nlm.nih.gov/pubmed/35314027
http://dx.doi.org/10.7554/eLife.71156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989416/
https://www.ncbi.nlm.nih.gov/pubmed/35314027
http://dx.doi.org/10.7554/eLife.71156

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