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IPRS: Leveraging Gene-Environment Interaction to Reconstruct Polygenic Risk Score

Background: Polygenic risk score (PRS) is widely regarded as a predictor of genetic susceptibility to disease, applied to individuals to predict the risk of disease occurrence. When the gene-environment (G×E) interaction is considered, the traditional PRS prediction model directly uses PRS to intera...

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Detalles Bibliográficos
Autores principales:	Tang, Yingdan, You, Dongfang, Yi, Honggang, Yang, Sheng, Zhao, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989431/ https://www.ncbi.nlm.nih.gov/pubmed/35401709 http://dx.doi.org/10.3389/fgene.2022.801397

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