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Intraoperative near-infrared molecular imaging for diagnostic thoracoscopy in difficult clinical scenario

Precise diagnosis in intrathoracic malignancies is paramount for adequate treatment planning. Standard approach is histologic analysis from targeted biopsy obtained with different invasive procedures. Rarely, in difficult clinical scenarios, even gold standard diagnostic procedures can be ineffectiv...

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Autores principales: Guerrera, Francesco, Femia, Federico, Lyberis, Paraskevas, Filosso, Pier Luigi, Lausi, Paolo Olivo, Ruffini, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Via Medica 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989446/
https://www.ncbi.nlm.nih.gov/pubmed/35402028
http://dx.doi.org/10.5603/RPOR.a2022.0008
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author Guerrera, Francesco
Femia, Federico
Lyberis, Paraskevas
Filosso, Pier Luigi
Lausi, Paolo Olivo
Ruffini, Enrico
author_facet Guerrera, Francesco
Femia, Federico
Lyberis, Paraskevas
Filosso, Pier Luigi
Lausi, Paolo Olivo
Ruffini, Enrico
author_sort Guerrera, Francesco
collection PubMed
description Precise diagnosis in intrathoracic malignancies is paramount for adequate treatment planning. Standard approach is histologic analysis from targeted biopsy obtained with different invasive procedures. Rarely, in difficult clinical scenarios, even gold standard diagnostic procedures can be ineffective in obtaining a satisfying result. Procedural developments and technological improvements applied to the chosen technique can be helpful to deal with such situation. We present two clinical cases of suspected intrathoracic malignancy in which repeated unsuccessful diagnostic procedures had already been attempted. We adopted a protocol based on intraoperative fluorescence during diagnostic thoracoscopy to increase diagnostic efficacy. In both cases we obtained a precise pathological diagnosis.
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spelling pubmed-89894462022-04-08 Intraoperative near-infrared molecular imaging for diagnostic thoracoscopy in difficult clinical scenario Guerrera, Francesco Femia, Federico Lyberis, Paraskevas Filosso, Pier Luigi Lausi, Paolo Olivo Ruffini, Enrico Rep Pract Oncol Radiother Technical Note Precise diagnosis in intrathoracic malignancies is paramount for adequate treatment planning. Standard approach is histologic analysis from targeted biopsy obtained with different invasive procedures. Rarely, in difficult clinical scenarios, even gold standard diagnostic procedures can be ineffective in obtaining a satisfying result. Procedural developments and technological improvements applied to the chosen technique can be helpful to deal with such situation. We present two clinical cases of suspected intrathoracic malignancy in which repeated unsuccessful diagnostic procedures had already been attempted. We adopted a protocol based on intraoperative fluorescence during diagnostic thoracoscopy to increase diagnostic efficacy. In both cases we obtained a precise pathological diagnosis. Via Medica 2022-03-22 /pmc/articles/PMC8989446/ /pubmed/35402028 http://dx.doi.org/10.5603/RPOR.a2022.0008 Text en © 2022 Greater Poland Cancer Centre https://creativecommons.org/licenses/by-nc-nd/4.0/This article is available in open access under Creative Common Attribution-Non-Commercial-No Derivatives 4.0 International (CC BY-NC-ND 4.0) license, allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially
spellingShingle Technical Note
Guerrera, Francesco
Femia, Federico
Lyberis, Paraskevas
Filosso, Pier Luigi
Lausi, Paolo Olivo
Ruffini, Enrico
Intraoperative near-infrared molecular imaging for diagnostic thoracoscopy in difficult clinical scenario
title Intraoperative near-infrared molecular imaging for diagnostic thoracoscopy in difficult clinical scenario
title_full Intraoperative near-infrared molecular imaging for diagnostic thoracoscopy in difficult clinical scenario
title_fullStr Intraoperative near-infrared molecular imaging for diagnostic thoracoscopy in difficult clinical scenario
title_full_unstemmed Intraoperative near-infrared molecular imaging for diagnostic thoracoscopy in difficult clinical scenario
title_short Intraoperative near-infrared molecular imaging for diagnostic thoracoscopy in difficult clinical scenario
title_sort intraoperative near-infrared molecular imaging for diagnostic thoracoscopy in difficult clinical scenario
topic Technical Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989446/
https://www.ncbi.nlm.nih.gov/pubmed/35402028
http://dx.doi.org/10.5603/RPOR.a2022.0008
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