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Dermatofibrosarcoma protuberans of the upper eyelid treated with surface mould high-dose-rate brachytherapy

Dermatofibrosarcoma protuberans (DFSP) is a rare spindle cell tumor, comprising less than 0.1% of all malignant neoplasms. The trunk is the most commonly affected area, followed by the extremities and the head and neck. Of the latter cases, involvement of the periorbital area has been infrequently r...

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Autores principales: Jamora, Kurl E., Cereno, Reno Eufemon P., Inocencio, Elrick T., Hizon, Vicente Francisco R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Via Medica 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989447/
https://www.ncbi.nlm.nih.gov/pubmed/35402039
http://dx.doi.org/10.5603/RPOR.a2021.0110
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author Jamora, Kurl E.
Cereno, Reno Eufemon P.
Inocencio, Elrick T.
Hizon, Vicente Francisco R.
author_facet Jamora, Kurl E.
Cereno, Reno Eufemon P.
Inocencio, Elrick T.
Hizon, Vicente Francisco R.
author_sort Jamora, Kurl E.
collection PubMed
description Dermatofibrosarcoma protuberans (DFSP) is a rare spindle cell tumor, comprising less than 0.1% of all malignant neoplasms. The trunk is the most commonly affected area, followed by the extremities and the head and neck. Of the latter cases, involvement of the periorbital area has been infrequently reported. Surgery is the cornerstone of treatment but is associated with a high rate of recurrence if margins remain close or positive. This rate has been shown to be considerably decreased by the use of adjuvant radiotherapy. However, most reported cases utilize external beam radiation therapy (EBRT ) in the treatment of DFSP, including those with primary periorbital locations. We report a case of a 40-year-old male, presenting with a small nodule on the right upper eyelid, diagnosed as DFSP with positive margins post-surgery and treated with adjuvant customized surface mould high-dose-rate (HDR) brachytherapy in a low-resource setting.
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spelling pubmed-89894472022-04-08 Dermatofibrosarcoma protuberans of the upper eyelid treated with surface mould high-dose-rate brachytherapy Jamora, Kurl E. Cereno, Reno Eufemon P. Inocencio, Elrick T. Hizon, Vicente Francisco R. Rep Pract Oncol Radiother Case Report Dermatofibrosarcoma protuberans (DFSP) is a rare spindle cell tumor, comprising less than 0.1% of all malignant neoplasms. The trunk is the most commonly affected area, followed by the extremities and the head and neck. Of the latter cases, involvement of the periorbital area has been infrequently reported. Surgery is the cornerstone of treatment but is associated with a high rate of recurrence if margins remain close or positive. This rate has been shown to be considerably decreased by the use of adjuvant radiotherapy. However, most reported cases utilize external beam radiation therapy (EBRT ) in the treatment of DFSP, including those with primary periorbital locations. We report a case of a 40-year-old male, presenting with a small nodule on the right upper eyelid, diagnosed as DFSP with positive margins post-surgery and treated with adjuvant customized surface mould high-dose-rate (HDR) brachytherapy in a low-resource setting. Via Medica 2022-03-22 /pmc/articles/PMC8989447/ /pubmed/35402039 http://dx.doi.org/10.5603/RPOR.a2021.0110 Text en © 2022 Greater Poland Cancer Centre https://creativecommons.org/licenses/by-nc-nd/4.0/This article is available in open access under Creative Common Attribution-Non-Commercial-No Derivatives 4.0 International (CC BY-NC-ND 4.0) license, allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially
spellingShingle Case Report
Jamora, Kurl E.
Cereno, Reno Eufemon P.
Inocencio, Elrick T.
Hizon, Vicente Francisco R.
Dermatofibrosarcoma protuberans of the upper eyelid treated with surface mould high-dose-rate brachytherapy
title Dermatofibrosarcoma protuberans of the upper eyelid treated with surface mould high-dose-rate brachytherapy
title_full Dermatofibrosarcoma protuberans of the upper eyelid treated with surface mould high-dose-rate brachytherapy
title_fullStr Dermatofibrosarcoma protuberans of the upper eyelid treated with surface mould high-dose-rate brachytherapy
title_full_unstemmed Dermatofibrosarcoma protuberans of the upper eyelid treated with surface mould high-dose-rate brachytherapy
title_short Dermatofibrosarcoma protuberans of the upper eyelid treated with surface mould high-dose-rate brachytherapy
title_sort dermatofibrosarcoma protuberans of the upper eyelid treated with surface mould high-dose-rate brachytherapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989447/
https://www.ncbi.nlm.nih.gov/pubmed/35402039
http://dx.doi.org/10.5603/RPOR.a2021.0110
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