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Retron reverse transcriptase termination and phage defense are dependent on host RNase H1
Retrons are bacterial retroelements that produce single-stranded, reverse-transcribed DNA (RT-DNA) that is a critical part of a newly discovered phage defense system. Short retron RT-DNAs are produced from larger, structured RNAs via a unique 2′-5′ initiation and a mechanism for precise termination...
Autores principales: | Palka, Christina, Fishman, Chloe B, Bhattarai-Kline, Santi, Myers, Samuel A, Shipman, Seth L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989520/ https://www.ncbi.nlm.nih.gov/pubmed/35293583 http://dx.doi.org/10.1093/nar/gkac177 |
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