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Retron reverse transcriptase termination and phage defense are dependent on host RNase H1

Retrons are bacterial retroelements that produce single-stranded, reverse-transcribed DNA (RT-DNA) that is a critical part of a newly discovered phage defense system. Short retron RT-DNAs are produced from larger, structured RNAs via a unique 2′-5′ initiation and a mechanism for precise termination...

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Detalles Bibliográficos
Autores principales:	Palka, Christina, Fishman, Chloe B, Bhattarai-Kline, Santi, Myers, Samuel A, Shipman, Seth L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	RNA and RNA-protein complexes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989520/ https://www.ncbi.nlm.nih.gov/pubmed/35293583 http://dx.doi.org/10.1093/nar/gkac177

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