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Molecular basis of crosstalk in nuclear receptors: heterodimerization between PXR and CAR and the implication in gene regulation

The 48 human nuclear receptors (NRs) form a superfamily of transcription factors that regulate major physiological and pathological processes. Emerging evidence suggests that NR crosstalk can fundamentally change our understanding of NR biology, but detailed molecular mechanisms of crosstalk are lac...

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Detalles Bibliográficos
Autores principales:	Bwayi, Monicah N, Garcia-Maldonado, Efren, Chai, Sergio C, Xie, Boer, Chodankar, Shirish, Huber, Andrew D, Wu, Jing, Annu, Kavya, Wright, William C, Lee, Hyeong-Min, Seetharaman, Jayaraman, Wang, Jingheng, Buchman, Cameron D, Peng, Junmin, Chen, Taosheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989523/ https://www.ncbi.nlm.nih.gov/pubmed/35212371 http://dx.doi.org/10.1093/nar/gkac133

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