Programmable manipulation of oligonucleotide–albumin interaction for elongated circulation time

Oligonucleotide (ON) therapeutics are emerging as a new generation of medicine with tremendous potential, but their clinical translation is hampered by inferior stability and short circulation time in the human body. Here, we report a general approach to manipulating the interaction between ONs and...

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Detalles Bibliográficos
Autores principales: Yang, Cai, Zhao, Haitao, Sun, Yang, Wang, Cheng, Geng, Xinyao, Wang, Ruowen, Tang, Lumin, Han, Da, Liu, Jianjun, Tan, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989545/
https://www.ncbi.nlm.nih.gov/pubmed/35293579
http://dx.doi.org/10.1093/nar/gkac156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989545/
https://www.ncbi.nlm.nih.gov/pubmed/35293579
http://dx.doi.org/10.1093/nar/gkac156

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