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8-oxodG accumulation within super-enhancers marks fragile CTCF-mediated chromatin loops

8-Oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG), a major product of the DNA oxidization process, has been proposed to have an epigenetic function in gene regulation and has been associated with genome instability. NGS-based methodologies are contributing to the characterization of the 8-oxodG function...

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Detalles Bibliográficos
Autores principales:	Scala, Giovanni, Gorini, Francesca, Ambrosio, Susanna, Chiariello, Andrea M, Nicodemi, Mario, Lania, Luigi, Majello, Barbara, Amente, Stefano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989568/ https://www.ncbi.nlm.nih.gov/pubmed/35234932 http://dx.doi.org/10.1093/nar/gkac143

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