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A Standardized Investigational Ki-67 Immunohistochemistry Assay Used to Assess High-Risk Early Breast Cancer Patients in the monarchE Phase 3 Clinical Study Identifies a Population With Greater Risk of Disease Recurrence When Treated With Endocrine Therapy Alone

The objectives were to develop a standardized Ki-67 immunohistochemistry (IHC) method for precise, robust, and reproducible assessment of patients with early breast cancer, and utilize this assay to evaluate patients participating in the monarchE study (NCT03155997). The Ki-67 assay was developed an...

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Detalles Bibliográficos
Autores principales: Polewski, Monika D., Nielsen, Gitte B., Gu, Ying, Weaver, Aaron T., Gegg, Gavin, Tabuena-Frolli, Siena, Cajaiba, Mariana, Hanks, Debra, Method, Michael, Press, Michael F., Gottstein, Claudia, Gruver, Aaron M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989635/
https://www.ncbi.nlm.nih.gov/pubmed/35384873
http://dx.doi.org/10.1097/PAI.0000000000001009