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A Standardized Investigational Ki-67 Immunohistochemistry Assay Used to Assess High-Risk Early Breast Cancer Patients in the monarchE Phase 3 Clinical Study Identifies a Population With Greater Risk of Disease Recurrence When Treated With Endocrine Therapy Alone
The objectives were to develop a standardized Ki-67 immunohistochemistry (IHC) method for precise, robust, and reproducible assessment of patients with early breast cancer, and utilize this assay to evaluate patients participating in the monarchE study (NCT03155997). The Ki-67 assay was developed an...
Autores principales: | Polewski, Monika D., Nielsen, Gitte B., Gu, Ying, Weaver, Aaron T., Gegg, Gavin, Tabuena-Frolli, Siena, Cajaiba, Mariana, Hanks, Debra, Method, Michael, Press, Michael F., Gottstein, Claudia, Gruver, Aaron M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989635/ https://www.ncbi.nlm.nih.gov/pubmed/35384873 http://dx.doi.org/10.1097/PAI.0000000000001009 |
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