3H-1,2-Dithiole-3-thione Suppresses LPS-induced Proinflammatory Responses in Macrophages: Potential Involvement of Antioxidant Induction, NF-κB, and Nrf2

Previously, we reported that 3H-1,2-dithiole-3-thione (D3T), an Nrf2 activator, acted as a potential chemoprotectant against lipopolysaccharide (LPS)-induced mortality in mice. In view of the critical involvement of macrophages in the pathogenesis of LPS-induced endotoxemia, in the present study, we...

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Detalles Bibliográficos
Autores principales: Zhu, Hong, Bui, An, Santo, Arben, Li, Y. Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989649/
https://www.ncbi.nlm.nih.gov/pubmed/35179677
http://dx.doi.org/10.1007/s11010-021-04331-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989649/
https://www.ncbi.nlm.nih.gov/pubmed/35179677
http://dx.doi.org/10.1007/s11010-021-04331-x

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