Hydroxychloroquine Alleviates EAU by Inhibiting Uveitogenic T Cells and Ameliorating Retinal Vascular Endothelial Cells Dysfunction

PURPOSE: Inflammation triggers the activation of CD4(+)T cells and the breakdown of blood–retinal barrier, thus contributing to the pathology of experimental autoimmune uveitis (EAU). We explored the anti-inflammatory effect of hydroxychloroquine (HCQ) on EAU and the potential mechanisms active in T...

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Detalles Bibliográficos
Autores principales: Hu, Yunwei, Li, Zuoyi, Chen, Guanyu, Li, Zhuang, Huang, Jun, Huang, Haixiang, Xie, Yanyan, Chen, Qian, Zhu, Wenjie, Wang, Minzhen, Chen, Jianping, Su, Wenru, Chen, Xiaoqing, Liang, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989724/
https://www.ncbi.nlm.nih.gov/pubmed/35401507
http://dx.doi.org/10.3389/fimmu.2022.859260

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