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Unique associations of pain frequency and pain-related worry with health-related quality of life in survivors of childhood cancer
INTRODUCTION: Pain is common during childhood cancer treatment, can persist into survivorship, and can negatively affect health-related quality of life in survivors of childhood cancers (SCCs). OBJECTIVE: The objective of this brief report was to assess pain frequency, pain-related worry, and their...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989778/ https://www.ncbi.nlm.nih.gov/pubmed/35415383 http://dx.doi.org/10.1097/PR9.0000000000001000 |
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author | Heathcote, Lauren C. Cunningham, Sarah J. Patton, Michaela Schulte, Fiona |
author_facet | Heathcote, Lauren C. Cunningham, Sarah J. Patton, Michaela Schulte, Fiona |
author_sort | Heathcote, Lauren C. |
collection | PubMed |
description | INTRODUCTION: Pain is common during childhood cancer treatment, can persist into survivorship, and can negatively affect health-related quality of life in survivors of childhood cancers (SCCs). OBJECTIVE: The objective of this brief report was to assess pain frequency, pain-related worry, and their (unique) associations with health-related quality of life in SCCs. METHODS: One hundred eleven SCCs (52% female individuals, M age: 17.67 years, range 8–25 years) completed self-report measures of pain frequency, pain-related worry, and health-related quality of life. RESULTS: More than two-thirds (70%) of SCCs reported pain in the previous month (M = 1.39, SD = 1.17), and 15% reported experiencing pain often or almost always. More than one-third (39%) reported worrying about pain as a sign of cancer recurrence (M = 0.73, SD = 1.07), and 9% reported worrying about pain a lot or a whole lot. In multivariate regression models that controlled for sex, age at diagnosis, and time off treatment, both pain frequency and pain-related worry were significantly associated with physical health-related quality of life, indicating that they contribute unique variance to health-related quality of life after childhood cancer. For emotional health-related quality of life, pain frequency was no longer a significant predictor once pain-related worry was added to the model, indicating that pain-related worry may be particularly important for understanding emotional health-related quality of life. CONCLUSION: Postcancer pain may contribute to health-related quality of life through multiple mechanisms, including by triggering concerns of recurrence. There is a need for clinical interventions that target both the frequency of pain (eg, behavioral interventions) and pain-related worry (eg, psychoeducation and cognitive interventions) to improve health-related quality of life after childhood cancer. |
format | Online Article Text |
id | pubmed-8989778 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wolters Kluwer |
record_format | MEDLINE/PubMed |
spelling | pubmed-89897782022-04-11 Unique associations of pain frequency and pain-related worry with health-related quality of life in survivors of childhood cancer Heathcote, Lauren C. Cunningham, Sarah J. Patton, Michaela Schulte, Fiona Pain Rep Cancer and Palliative INTRODUCTION: Pain is common during childhood cancer treatment, can persist into survivorship, and can negatively affect health-related quality of life in survivors of childhood cancers (SCCs). OBJECTIVE: The objective of this brief report was to assess pain frequency, pain-related worry, and their (unique) associations with health-related quality of life in SCCs. METHODS: One hundred eleven SCCs (52% female individuals, M age: 17.67 years, range 8–25 years) completed self-report measures of pain frequency, pain-related worry, and health-related quality of life. RESULTS: More than two-thirds (70%) of SCCs reported pain in the previous month (M = 1.39, SD = 1.17), and 15% reported experiencing pain often or almost always. More than one-third (39%) reported worrying about pain as a sign of cancer recurrence (M = 0.73, SD = 1.07), and 9% reported worrying about pain a lot or a whole lot. In multivariate regression models that controlled for sex, age at diagnosis, and time off treatment, both pain frequency and pain-related worry were significantly associated with physical health-related quality of life, indicating that they contribute unique variance to health-related quality of life after childhood cancer. For emotional health-related quality of life, pain frequency was no longer a significant predictor once pain-related worry was added to the model, indicating that pain-related worry may be particularly important for understanding emotional health-related quality of life. CONCLUSION: Postcancer pain may contribute to health-related quality of life through multiple mechanisms, including by triggering concerns of recurrence. There is a need for clinical interventions that target both the frequency of pain (eg, behavioral interventions) and pain-related worry (eg, psychoeducation and cognitive interventions) to improve health-related quality of life after childhood cancer. Wolters Kluwer 2022-04-05 /pmc/articles/PMC8989778/ /pubmed/35415383 http://dx.doi.org/10.1097/PR9.0000000000001000 Text en Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The International Association for the Study of Pain. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Cancer and Palliative Heathcote, Lauren C. Cunningham, Sarah J. Patton, Michaela Schulte, Fiona Unique associations of pain frequency and pain-related worry with health-related quality of life in survivors of childhood cancer |
title | Unique associations of pain frequency and pain-related worry with health-related quality of life in survivors of childhood cancer |
title_full | Unique associations of pain frequency and pain-related worry with health-related quality of life in survivors of childhood cancer |
title_fullStr | Unique associations of pain frequency and pain-related worry with health-related quality of life in survivors of childhood cancer |
title_full_unstemmed | Unique associations of pain frequency and pain-related worry with health-related quality of life in survivors of childhood cancer |
title_short | Unique associations of pain frequency and pain-related worry with health-related quality of life in survivors of childhood cancer |
title_sort | unique associations of pain frequency and pain-related worry with health-related quality of life in survivors of childhood cancer |
topic | Cancer and Palliative |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989778/ https://www.ncbi.nlm.nih.gov/pubmed/35415383 http://dx.doi.org/10.1097/PR9.0000000000001000 |
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