The SNPs of mitochondrial DNA displacement loop region and mitochondrial DNA copy number associated with risk of polymyositis and dermatomyositis

Oxidative damage-induced mitochondrial dysfunction may activate muscle catabolism and autophagy pathways to initiate muscle weakening in idiopathic inflammatory myopathies (IIMs). In this study, Single nucleotide polymorphisms (SNPs) in the mitochondrial displacement loop (D-loop) and mitochondrial...

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Detalles Bibliográficos
Autores principales: Zhao, Yufei, Peng, Chenxing, Lai, Ruixue, Zhang, Jingjing, Zhang, Xiaoyun, Guo, Zhanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990067/
https://www.ncbi.nlm.nih.gov/pubmed/35393495
http://dx.doi.org/10.1038/s41598-022-09943-x

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