Virally programmed extracellular vesicles sensitize cancer cells to oncolytic virus and small molecule therapy

Recent advances in cancer therapeutics clearly demonstrate the need for innovative multiplex therapies that attack the tumour on multiple fronts. Oncolytic or “cancer-killing” viruses (OVs) represent up-and-coming multi-mechanistic immunotherapeutic drugs for the treatment of cancer. In this study,...

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Detalles Bibliográficos
Autores principales: Wedge, Marie-Eve, Jennings, Victoria A., Crupi, Mathieu J. F., Poutou, Joanna, Jamieson, Taylor, Pelin, Adrian, Pugliese, Giuseppe, de Souza, Christiano Tanese, Petryk, Julia, Laight, Brian J., Boileau, Meaghan, Taha, Zaid, Alluqmani, Nouf, McKay, Hayley E., Pikor, Larissa, Khan, Sarwat Tahsin, Azad, Taha, Rezaei, Reza, Austin, Bradley, He, Xiaohong, Mansfield, David, Rose, Elaine, Brown, Emily E. F., Crawford, Natalie, Alkayyal, Almohanad, Surendran, Abera, Singaravelu, Ragunath, Roy, Dominic G., Migneco, Gemma, McSweeney, Benjamin, Cottee, Mary Lynn, Jacobus, Egon J., Keller, Brian A., Yamaguchi, Takafumi N., Boutros, Paul C., Geoffrion, Michele, Rayner, Katey J., Chatterjee, Avijit, Auer, Rebecca C., Diallo, Jean-Simon, Gibbings, Derrick, tenOever, Benjamin R., Melcher, Alan, Bell, John C., Ilkow, Carolina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990073/
https://www.ncbi.nlm.nih.gov/pubmed/35393414
http://dx.doi.org/10.1038/s41467-022-29526-8

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