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Comparison of Therapeutic Effects of PVP and PKP Combined With Triple Medication on Mild and Moderate Osteoporotic Vertebral Compression Fracture in the Elderly
OBJECTIVE: To compare and analyze the therapeutic effect of percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) combined with triple therapy on elderly patients with mild to moderate osteoporotic vertebral compression fractures (OVCF). METHODS: A total of 114 cases of elderly patien...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990093/ https://www.ncbi.nlm.nih.gov/pubmed/35402473 http://dx.doi.org/10.3389/fsurg.2021.663099 |
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author | Zhou, Yi Jiang, Jiang Gu, Fulong Mi, Daguo |
author_facet | Zhou, Yi Jiang, Jiang Gu, Fulong Mi, Daguo |
author_sort | Zhou, Yi |
collection | PubMed |
description | OBJECTIVE: To compare and analyze the therapeutic effect of percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) combined with triple therapy on elderly patients with mild to moderate osteoporotic vertebral compression fractures (OVCF). METHODS: A total of 114 cases of elderly patients with mild to moderate osteoporotic vertebral compression fractures were identified as research subjects in our hospital from January 2017 to January 2018, and a total of 136 vertebrae were included. The patients who underwent PVP operation were included as the control group with 67 injured vertebrae, and the patients who underwent PKP operation were included as the experimental group with 69 injured vertebrae. RESULTS: The operation time and bone cement injection volume of the experimental group were significantly higher than the control group. The visual analog scale (VAS) scores of the two groups at 3 months and 6 months after operation were lower than those before operation, with lower VAS scores observed in the experimental group at 3 months and 6 months after operation. The anterior height of the vertebral body in the experimental group was higher than that of the control group. The experimental group outperformed the control group in the incidence of postoperative complications. The postoperative Oswestry dysfunction index (ODI) scores of the two groups were lower before the operation, in which the experimental group had lower scores than the control group (P < 0.05). CONCLUSION: PVP and PKP combined with postoperative triple therapy can achieve a promising analgesic effect. PKP has a higher volume of bone cement injection volume, and a lower incidence of complications, which gives rise to a better vertebral body recovery height than that of PVP, with rapid postoperative body function recovery and good quality of life. |
format | Online Article Text |
id | pubmed-8990093 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-89900932022-04-09 Comparison of Therapeutic Effects of PVP and PKP Combined With Triple Medication on Mild and Moderate Osteoporotic Vertebral Compression Fracture in the Elderly Zhou, Yi Jiang, Jiang Gu, Fulong Mi, Daguo Front Surg Surgery OBJECTIVE: To compare and analyze the therapeutic effect of percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) combined with triple therapy on elderly patients with mild to moderate osteoporotic vertebral compression fractures (OVCF). METHODS: A total of 114 cases of elderly patients with mild to moderate osteoporotic vertebral compression fractures were identified as research subjects in our hospital from January 2017 to January 2018, and a total of 136 vertebrae were included. The patients who underwent PVP operation were included as the control group with 67 injured vertebrae, and the patients who underwent PKP operation were included as the experimental group with 69 injured vertebrae. RESULTS: The operation time and bone cement injection volume of the experimental group were significantly higher than the control group. The visual analog scale (VAS) scores of the two groups at 3 months and 6 months after operation were lower than those before operation, with lower VAS scores observed in the experimental group at 3 months and 6 months after operation. The anterior height of the vertebral body in the experimental group was higher than that of the control group. The experimental group outperformed the control group in the incidence of postoperative complications. The postoperative Oswestry dysfunction index (ODI) scores of the two groups were lower before the operation, in which the experimental group had lower scores than the control group (P < 0.05). CONCLUSION: PVP and PKP combined with postoperative triple therapy can achieve a promising analgesic effect. PKP has a higher volume of bone cement injection volume, and a lower incidence of complications, which gives rise to a better vertebral body recovery height than that of PVP, with rapid postoperative body function recovery and good quality of life. Frontiers Media S.A. 2022-03-25 /pmc/articles/PMC8990093/ /pubmed/35402473 http://dx.doi.org/10.3389/fsurg.2021.663099 Text en Copyright © 2022 Zhou, Jiang, Gu and Mi. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Surgery Zhou, Yi Jiang, Jiang Gu, Fulong Mi, Daguo Comparison of Therapeutic Effects of PVP and PKP Combined With Triple Medication on Mild and Moderate Osteoporotic Vertebral Compression Fracture in the Elderly |
title | Comparison of Therapeutic Effects of PVP and PKP Combined With Triple Medication on Mild and Moderate Osteoporotic Vertebral Compression Fracture in the Elderly |
title_full | Comparison of Therapeutic Effects of PVP and PKP Combined With Triple Medication on Mild and Moderate Osteoporotic Vertebral Compression Fracture in the Elderly |
title_fullStr | Comparison of Therapeutic Effects of PVP and PKP Combined With Triple Medication on Mild and Moderate Osteoporotic Vertebral Compression Fracture in the Elderly |
title_full_unstemmed | Comparison of Therapeutic Effects of PVP and PKP Combined With Triple Medication on Mild and Moderate Osteoporotic Vertebral Compression Fracture in the Elderly |
title_short | Comparison of Therapeutic Effects of PVP and PKP Combined With Triple Medication on Mild and Moderate Osteoporotic Vertebral Compression Fracture in the Elderly |
title_sort | comparison of therapeutic effects of pvp and pkp combined with triple medication on mild and moderate osteoporotic vertebral compression fracture in the elderly |
topic | Surgery |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990093/ https://www.ncbi.nlm.nih.gov/pubmed/35402473 http://dx.doi.org/10.3389/fsurg.2021.663099 |
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