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The interleukin-1 axis and the tumor immune microenvironment in pancreatic ductal adenocarcinoma
Interleukin-1 (IL-1) plays a key role in carcinogenesis and several IL-1-targeted therapeutics are under investigation for the treatment of pancreatic ductal adenocarcinoma (PDAC). We sought to broaden our understanding of how the family of IL-1 ligands and receptors impact the tumor immune landscap...
Autores principales: | Herremans, Kelly M., Szymkiewicz, Dominique D., Riner, Andrea N., Bohan, Riley P., Tushoski, Gerik W., Davidson, Aaron M., Lou, XiangYang, Leong, Man Chong, Dean, Bayli DiVita, Gerber, Michael, Underwood, Patrick W., Han, Song, Hughes, Steven J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990176/ https://www.ncbi.nlm.nih.gov/pubmed/35395492 http://dx.doi.org/10.1016/j.neo.2022.100789 |
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