ONP-302 Nanoparticles Inhibit Tumor Growth By Altering Tumor-Associated Macrophages And Cancer-Associated Fibroblasts

In this study, we evaluated the ability of negatively charged bio-degradable nanoparticles, ONP- 302, to inhibit tumor growth. Therapeutic treatment with ONP-302 in vivo resulted in a marked delay in tumor growth in three different syngeneic tumor models in immunocompetent mice. ONP- 302 efficacy pe...

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Detalles Bibliográficos
Autores principales: Donthireddy, Laxminarasimha, Vonteddu, Prashanthi, Murthy, Tushar, Kwak, Taekyoung, Eraslan, Rukiye-Nazan, Podojil, Joseph R., Elhofy, Adam, Boyne, Michael T., Puisis, John J., Veglia, Filippo, Singh, Surya S., Dotiwala, Farokh, Montaner, Luis J., Gabrilovich, Dmitry I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990435/
https://www.ncbi.nlm.nih.gov/pubmed/35399717
http://dx.doi.org/10.7150/jca.69338

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