Cargando…

Minocycline binds and inhibits LYN activity to prevent STAT3-meditated metastasis of colorectal cancer

Colorectal cancer (CRC) is one of the most common malignancies worldwide. Metastasis is a major cause of CRC recurrence and mortality. Several antibiotic drugs have been reported to exert potential anticancer activities, however, whether and how the tetracycline antibiotic minocycline exhibit tumor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Ling, Yang, Jing, Liu, Hua, Lan, Jingbin, Xu, Ying, Wu, Xiaobo, Mao, Yushan, Wu, Dongming, Pan, Kejian, Zhang, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990469/ https://www.ncbi.nlm.nih.gov/pubmed/35414768 http://dx.doi.org/10.7150/ijbs.70708

Ejemplares similares

Essential Role of Lyn in Fibrosis
por: Pham, Hung, et al.
Publicado: (2016)

Immune Characteristics of LYN in Tumor Microenvironment of Gliomas
por: Jiang, Chonghua, et al.
Publicado: (2022)

Three Potential Tumor Markers Promote Metastasis and Recurrence of Colorectal Cancer by Regulating the Inflammatory Response: ADAM8, LYN, and S100A9
por: Liu, Jiawei, et al.
Publicado: (2022)

Lyn regulates mucus secretion and MUC5AC via the STAT6 signaling pathway during allergic airway inflammation
por: Wang, Xiaoyun, et al.
Publicado: (2017)

Awards for Lyn Evans and Philippe Lebrun
Publicado: (2007)

The LHC Adventure -- Dr. Lyn Evans
por: CERN. Geneva
Publicado: (2009)

Illusory Temporal Binding in Meditators
por: Lush, Peter, et al.
Publicado: (2016)

Lyn is involved in CD24-induced ERK1/2 activation in colorectal cancer
por: Su, Ning, et al.
Publicado: (2012)

Lyn regulates epithelial–mesenchymal transition in CS-exposed model through Smad2/3 signaling
por: Liang, Xiaobo, et al.
Publicado: (2019)

HMGB1 mediates lipopolysaccharide-induced inflammation via interacting with GPX4 in colon cancer cells
por: Yang, Yuhan, et al.
Publicado: (2020)

Lyn modulates Claudin-2 expression and is a therapeutic target for breast cancer liver metastasis
por: Tabariès, Sébastien, et al.
Publicado: (2015)

Functions of the Lyn tyrosine kinase in health and disease
por: Ingley, Evan
Publicado: (2012)

Lyn Evans, l'homme du LHC
Publicado: (2009)

Correction: Lyn is involved in CD24-induced ERK1/2 activation in colorectal cancer
por: Su, Ning, et al.
Publicado: (2012)

Lyn kinase regulates egress of flaviviruses in autophagosome-derived organelles
por: Li, Ming Yuan, et al.
Publicado: (2020)

Aspartoacylase suppresses prostate cancer progression by blocking LYN activation
por: Weng, Hong, et al.
Publicado: (2023)

SIRT1 activation by minocycline on regulation of microglial polarization homeostasis
por: Wu, Ling-Hsuan, et al.
Publicado: (2020)

Therapeutic targeting of Lyn kinase to treat chorea-acanthocytosis
por: Peikert, Kevin, et al.
Publicado: (2021)

Testicular Pain Associated With Minocycline Use
por: Kucherov, Victor, et al.
Publicado: (2015)

FOXM1/DVL2/Snail axis drives metastasis and chemoresistance of colorectal cancer
por: Yang, Yuhan, et al.
Publicado: (2020)

GPI-anchored receptor clusters transiently recruit Lyn and Gα for temporary cluster immobilization and Lyn activation: single-molecule tracking study 1
por: Suzuki, Kenichi G.N., et al.
Publicado: (2007)

Recruitment of Lyn from endomembranes to the plasma membrane through calcium-dependent cell-cell interactions upon polarization of inducible Lyn-expressing MDCK cells
por: Morinaga, Takao, et al.
Publicado: (2017)

Deregulated Expression of SRC, LYN and CKB Kinases by DNA Methylation and Its Potential Role in Gastric Cancer Invasiveness and Metastasis
por: Mello, Adriano Azevedo, et al.
Publicado: (2015)

Lyn kinase represses mucus hypersecretion by regulating IL-13-induced endoplasmic reticulum stress in asthma
por: Wang, Xing, et al.
Publicado: (2016)

Minocycline-induced hyperpigmentation
por: Fiscus, Valena, et al.
Publicado: (2014)

Sustained Activation of Lyn Tyrosine Kinase In Vivo Leads to Autoimmunity
por: Hibbs, Margaret L., et al.
Publicado: (2002)

Inhibition of the B Cell by CD22: A Requirement for Lyn
por: Smith, Kenneth G.C., et al.
Publicado: (1998)

Lyn Evans, Peter jenni, Tejinder Virdee: BIG BANG
por: Giussani, Bruno
Publicado: (2007)

LynA regulates an inflammation-sensitive signaling checkpoint in macrophages
por: Freedman, Tanya S, et al.
Publicado: (2015)

A dominant function of LynB kinase in preventing autoimmunity
por: Brian, Ben F., et al.
Publicado: (2022)

Metformin reverse minocycline to inhibit minocycline-resistant Acinetobacter baumannii by destroy the outer membrane and enhance membrane potential in vitro
por: Guo, Tingting, et al.
Publicado: (2022)

Minocycline and antipsychotics inhibit inflammatory responses in BV-2 microglia activated by LPS via regulating the MAPKs/ JAK-STAT signaling pathway
por: Long, Yujun, et al.
Publicado: (2023)

Meditation
por: Srinivasan, Narayanan
Publicado: (2019)

MEDITATION/
por: Joe Pass

Meditations on …
por: Wray, K. Brad
Publicado: (2021)

Minocycline attenuates interferon-α-induced impairments in rat fear extinction
por: Bi, Qiang, et al.
Publicado: (2016)

Independent and Opposing Roles For Btk and Lyn in B and Myeloid Signaling Pathways
por: Satterthwaite, Anne B., et al.
Publicado: (1998)

Negative Regulation of Immunoglobulin E–dependent Allergic Responses by Lyn Kinase
por: Odom, Sandra, et al.
Publicado: (2004)

Lyn is a redox sensor that mediates leukocyte wound attraction in vivo
por: Yoo, Sa Kan, et al.
Publicado: (2011)

Dr Lyn Evans' hopes for CERN Large Hadron Collider project
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_i85fi77oba8k97d3pfpdfs6koi