MGP promotes CD8(+) T cell exhaustion by activating the NF-κB pathway leading to liver metastasis of colorectal cancer

Matrix Gla protein (MGP) was originally reported as a physiological suppressor of ectopia calcification and has also been reported to be associated with cancer. However, the relation between the biological functions of MGP and the immune response in colorectal cancer (CRC) remains unclear. Here, we...

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Detalles Bibliográficos
Autores principales: Rong, Dawei, Sun, Guangshun, Zheng, Zhiying, Liu, Li, Chen, Xiaoyuan, Wu, Fan, Gu, Yichao, Dai, Yongjiu, Zhong, Weizhe, Hao, Xiaopei, Zhang, Chuanyong, Pan, Xiongxiong, Tang, Jinhai, Tang, Weiwei, Wang, Xuehao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990480/
https://www.ncbi.nlm.nih.gov/pubmed/35414780
http://dx.doi.org/10.7150/ijbs.70137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990480/
https://www.ncbi.nlm.nih.gov/pubmed/35414780
http://dx.doi.org/10.7150/ijbs.70137

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