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MGP promotes CD8(+) T cell exhaustion by activating the NF-κB pathway leading to liver metastasis of colorectal cancer
Matrix Gla protein (MGP) was originally reported as a physiological suppressor of ectopia calcification and has also been reported to be associated with cancer. However, the relation between the biological functions of MGP and the immune response in colorectal cancer (CRC) remains unclear. Here, we...
Autores principales: | Rong, Dawei, Sun, Guangshun, Zheng, Zhiying, Liu, Li, Chen, Xiaoyuan, Wu, Fan, Gu, Yichao, Dai, Yongjiu, Zhong, Weizhe, Hao, Xiaopei, Zhang, Chuanyong, Pan, Xiongxiong, Tang, Jinhai, Tang, Weiwei, Wang, Xuehao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990480/ https://www.ncbi.nlm.nih.gov/pubmed/35414780 http://dx.doi.org/10.7150/ijbs.70137 |
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