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Epidemiology of traumatic spinal cord injury: a large population-based study

STUDY DESIGN: A retrospective population-based study. OBJECTIVES: Describe the incidence of traumatic spinal cord injury (TSCI) and mortality risks, based on the characteristics of the patient, anatomical level of the lesion, setting/cause of the injury, and type of healthcare support received withi...

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Autores principales: Barbiellini Amidei, Claudio, Salmaso, Laura, Bellio, Stefania, Saia, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990493/
https://www.ncbi.nlm.nih.gov/pubmed/35396455
http://dx.doi.org/10.1038/s41393-022-00795-w
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author Barbiellini Amidei, Claudio
Salmaso, Laura
Bellio, Stefania
Saia, Mario
author_facet Barbiellini Amidei, Claudio
Salmaso, Laura
Bellio, Stefania
Saia, Mario
author_sort Barbiellini Amidei, Claudio
collection PubMed
description STUDY DESIGN: A retrospective population-based study. OBJECTIVES: Describe the incidence of traumatic spinal cord injury (TSCI) and mortality risks, based on the characteristics of the patient, anatomical level of the lesion, setting/cause of the injury, and type of healthcare support received within the regional trauma network (highly specialized trauma center or spoke hospital). SETTING: Between 2011 and 2020, 1303 patients with incident TSCI were identified in a population of 4.9 million inhabitants. METHODS: Hospital discharge records and mortality records were used to identify patients and outcomes. Cox regression models were fitted to estimate mortality risks across several subgroups. RESULTS: Over the past decade, age-sex-standardized TSCI incidence rates remained stable with 26.5 cases (95% CI, 25.0–27.9) per 1,000,000 inhabitants (mean age 59.2 years) and most cases were males (68.3%). Incidence was directly associated with age while the male to female ratio was inversely related. Most TSCIs were cervical lesions (52.1%), and the most common cause of injury were traffic crashes (29.9%) followed by occupational accidents (29.8%). Sex, cause of the trauma, or inpatient hospital management were not associated with an increased risk of death. Mortality rates were greater for cervical lesions, and increased with age, remaining stably high among older individuals even 12 months after the accident. One-month mortality risk was significantly higher at ≥75 years compared to <55 years (adjusted HR 9.14 (95% CI, 4.17–20.03)). CONCLUSION: Public health policies should aim at reducing preventable TSCIs, and special attention should be drawn to long-term management of elderly patients in the attempt to decrease mortality rates.
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spelling pubmed-89904932022-04-11 Epidemiology of traumatic spinal cord injury: a large population-based study Barbiellini Amidei, Claudio Salmaso, Laura Bellio, Stefania Saia, Mario Spinal Cord Article STUDY DESIGN: A retrospective population-based study. OBJECTIVES: Describe the incidence of traumatic spinal cord injury (TSCI) and mortality risks, based on the characteristics of the patient, anatomical level of the lesion, setting/cause of the injury, and type of healthcare support received within the regional trauma network (highly specialized trauma center or spoke hospital). SETTING: Between 2011 and 2020, 1303 patients with incident TSCI were identified in a population of 4.9 million inhabitants. METHODS: Hospital discharge records and mortality records were used to identify patients and outcomes. Cox regression models were fitted to estimate mortality risks across several subgroups. RESULTS: Over the past decade, age-sex-standardized TSCI incidence rates remained stable with 26.5 cases (95% CI, 25.0–27.9) per 1,000,000 inhabitants (mean age 59.2 years) and most cases were males (68.3%). Incidence was directly associated with age while the male to female ratio was inversely related. Most TSCIs were cervical lesions (52.1%), and the most common cause of injury were traffic crashes (29.9%) followed by occupational accidents (29.8%). Sex, cause of the trauma, or inpatient hospital management were not associated with an increased risk of death. Mortality rates were greater for cervical lesions, and increased with age, remaining stably high among older individuals even 12 months after the accident. One-month mortality risk was significantly higher at ≥75 years compared to <55 years (adjusted HR 9.14 (95% CI, 4.17–20.03)). CONCLUSION: Public health policies should aim at reducing preventable TSCIs, and special attention should be drawn to long-term management of elderly patients in the attempt to decrease mortality rates. Nature Publishing Group UK 2022-04-08 2022 /pmc/articles/PMC8990493/ /pubmed/35396455 http://dx.doi.org/10.1038/s41393-022-00795-w Text en © The Author(s), under exclusive licence to International Spinal Cord Society 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Barbiellini Amidei, Claudio
Salmaso, Laura
Bellio, Stefania
Saia, Mario
Epidemiology of traumatic spinal cord injury: a large population-based study
title Epidemiology of traumatic spinal cord injury: a large population-based study
title_full Epidemiology of traumatic spinal cord injury: a large population-based study
title_fullStr Epidemiology of traumatic spinal cord injury: a large population-based study
title_full_unstemmed Epidemiology of traumatic spinal cord injury: a large population-based study
title_short Epidemiology of traumatic spinal cord injury: a large population-based study
title_sort epidemiology of traumatic spinal cord injury: a large population-based study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990493/
https://www.ncbi.nlm.nih.gov/pubmed/35396455
http://dx.doi.org/10.1038/s41393-022-00795-w
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