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HSP90/IKK‐rich small extracellular vesicles activate pro‐angiogenic melanoma‐associated fibroblasts via the NF‐κB/CXCL1 axis

Hypoxia is a main feature of most solid tumors, but how melanoma cells under hypoxic conditions exploit tumor microenvironment (TME) to facilitate tumor progression remains poorly understood. In this study, we found that hypoxic melanoma‐derived small extracellular vesicles (sEVs) could improve the...

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Detalles Bibliográficos
Autores principales: Tang, Hokeung, Zhou, Xiaocheng, Zhao, Xiaoping, Luo, Xinyue, Luo, Tingting, Chen, Yang, Liang, Weilian, Jiang, Erhui, Liu, Ke, Shao, Zhe, Shang, Zhengjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990732/
https://www.ncbi.nlm.nih.gov/pubmed/35043517
http://dx.doi.org/10.1111/cas.15271