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Bax/Bcl-2 Cascade Is Regulated by the EGFR Pathway: Therapeutic Targeting of Non-Small Cell Lung Cancer

Non-small cell lung carcinoma (NSCLC) comprises 80%–85% of lung cancer cases. EGFR is involved in several cancer developments, including NSCLC. The EGFR pathway regulates the Bax/Bcl-2 cascade in NSCLC. Increasing understanding of the molecular mechanisms of fundamental tumor progression has guided...

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Detalles Bibliográficos
Autores principales: Alam, Manzar, Alam, Shoaib, Shamsi, Anas, Adnan, Mohd, Elasbali, Abdelbaset Mohamed, Al-Soud, Waleed Abu, Alreshidi, Mousa, Hawsawi, Yousef MohammedRabaa, Tippana, Anitha, Pasupuleti, Visweswara Rao, Hassan, Md. Imtaiyaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990771/
https://www.ncbi.nlm.nih.gov/pubmed/35402265
http://dx.doi.org/10.3389/fonc.2022.869672

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