Combining EGFR-TKI With SAHA Overcomes EGFR-TKI-Acquired Resistance by Reducing the Protective Autophagy in Non-Small Cell Lung Cancer

Nowadays, lung cancer has the highest mortality worldwide. The emergence of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) has greatly improved the survival of patients with non-small cell lung cancer (NSCLC) having EGFR-TKI-sensitive mutations. Unfortunately, acquired res...

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Detalles Bibliográficos
Autores principales: Cao, Peijun, Li, Yongwen, Shi, Ruifeng, Yuan, Yin, Gong, Hao, Zhu, Guangsheng, Zhang, Zihe, Chen, Chen, Zhang, Hongbing, Liu, Minghui, Pan, Zhenhua, Liu, Hongyu, Chen, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990828/
https://www.ncbi.nlm.nih.gov/pubmed/35402377
http://dx.doi.org/10.3389/fchem.2022.837987

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