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Divergent Cardiac Effects of Angiotensin II and Isoproterenol Following Juvenile Exposure to Doxorubicin

Hypertension is the most significant risk factor for heart failure in doxorubicin (DOX)-treated childhood cancer survivors. We previously developed a two-hit mouse model of juvenile DOX-induced latent cardiotoxicity that is exacerbated by adult-onset angiotensin II (ANGII)-induced hypertension. It i...

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Detalles Bibliográficos
Autores principales:	Agostinucci, Kevin, Grant, Marianne K. O., Seelig, Davis, Yücel, Doğacan, van Berlo, Jop, Bartolomucci, Alessandro, Dyck, Jason R. B., Zordoky, Beshay N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990895/ https://www.ncbi.nlm.nih.gov/pubmed/35402534 http://dx.doi.org/10.3389/fcvm.2022.742193

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