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A Comprehensive Review of BET Protein Biochemistry, Physiology, and Pathological Roles

Epigenetic modifications, specifically acetylation of histone plays a decisive role in gene regulation and transcription of normal cellular mechanisms and pathological conditions. The bromodomain and extraterminal (BET) proteins (BRD2, BRD3, BRD4, and BRDT), being epigenetic readers, ligate to acety...

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Detalles Bibliográficos
Autores principales: Ali, Hafiz Akbar, Li, Yalan, Bilal, Akram Hafiz Muhammad, Qin, Tingting, Yuan, Ziqiao, Zhao, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990909/
https://www.ncbi.nlm.nih.gov/pubmed/35401196
http://dx.doi.org/10.3389/fphar.2022.818891