Deviations From the Ideal Plasma Volume and Isolated Tricuspid Valve Surgery—Paving the Way for New Risk Stratification Parameters

BACKGROUND: Congestion and plasma volume expansion are important features of heart failure, whose prognostic significance has been investigated in a range of surgical and non-surgical settings. The aim of this study was to evaluate the value of the estimated plasma volume status (ePVS) in patients u...

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Autores principales: Hasimbegovic, Ena, Russo, Marco, Andreas, Martin, Werner, Paul, Coti, Iuliana, Wiedemann, Dominik, Kocher, Alfred, Laufer, Günther, Hofer, Benedikt S., Mach, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990912/
https://www.ncbi.nlm.nih.gov/pubmed/35402525
http://dx.doi.org/10.3389/fcvm.2022.849972
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author Hasimbegovic, Ena
Russo, Marco
Andreas, Martin
Werner, Paul
Coti, Iuliana
Wiedemann, Dominik
Kocher, Alfred
Laufer, Günther
Hofer, Benedikt S.
Mach, Markus
author_facet Hasimbegovic, Ena
Russo, Marco
Andreas, Martin
Werner, Paul
Coti, Iuliana
Wiedemann, Dominik
Kocher, Alfred
Laufer, Günther
Hofer, Benedikt S.
Mach, Markus
author_sort Hasimbegovic, Ena
collection PubMed
description BACKGROUND: Congestion and plasma volume expansion are important features of heart failure, whose prognostic significance has been investigated in a range of surgical and non-surgical settings. The aim of this study was to evaluate the value of the estimated plasma volume status (ePVS) in patients undergoing isolated tricuspid valve surgery. METHODS: This study included patients who underwent isolated tricuspid valve surgery at the Vienna General Hospital (Austria) between July 2008 and November 2018. The PVS cut-off was calculated using ROC analysis and Youden's Index. RESULTS: Eighty eight patients (median age: 58 [IQR: 35-70] years; 44.3% male; 75.6% NYHA III/IV; median EuroSCORE II 2.65 [IQR: 1.70-5.10]; 33.0% endocarditis-related regurgitation; 60.2% isolated repair; 39.8% isolated replacement) were included in this study. Patients who died within 1 year following surgery had significantly higher baseline ePVS values than survivors (median ePVS 5.29 [IQR: −1.55-13.55] vs. −3.68 [IQR: −10.92-4.22]; p = 0.005). During a median actuarial follow-up of 3.02 (IQR: 0.36-6.80) years, patients with a preoperative ePVS ≥ −4.17 had a significantly increased mortality (log-rank p = 0.006). CONCLUSIONS: ePVS is an easily obtainable risk parameter for patients undergoing isolated tricuspid valve surgery capable of predicting mid- and long-term outcomes after isolated tricuspid valve surgery.
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spelling pubmed-89909122022-04-09 Deviations From the Ideal Plasma Volume and Isolated Tricuspid Valve Surgery—Paving the Way for New Risk Stratification Parameters Hasimbegovic, Ena Russo, Marco Andreas, Martin Werner, Paul Coti, Iuliana Wiedemann, Dominik Kocher, Alfred Laufer, Günther Hofer, Benedikt S. Mach, Markus Front Cardiovasc Med Cardiovascular Medicine BACKGROUND: Congestion and plasma volume expansion are important features of heart failure, whose prognostic significance has been investigated in a range of surgical and non-surgical settings. The aim of this study was to evaluate the value of the estimated plasma volume status (ePVS) in patients undergoing isolated tricuspid valve surgery. METHODS: This study included patients who underwent isolated tricuspid valve surgery at the Vienna General Hospital (Austria) between July 2008 and November 2018. The PVS cut-off was calculated using ROC analysis and Youden's Index. RESULTS: Eighty eight patients (median age: 58 [IQR: 35-70] years; 44.3% male; 75.6% NYHA III/IV; median EuroSCORE II 2.65 [IQR: 1.70-5.10]; 33.0% endocarditis-related regurgitation; 60.2% isolated repair; 39.8% isolated replacement) were included in this study. Patients who died within 1 year following surgery had significantly higher baseline ePVS values than survivors (median ePVS 5.29 [IQR: −1.55-13.55] vs. −3.68 [IQR: −10.92-4.22]; p = 0.005). During a median actuarial follow-up of 3.02 (IQR: 0.36-6.80) years, patients with a preoperative ePVS ≥ −4.17 had a significantly increased mortality (log-rank p = 0.006). CONCLUSIONS: ePVS is an easily obtainable risk parameter for patients undergoing isolated tricuspid valve surgery capable of predicting mid- and long-term outcomes after isolated tricuspid valve surgery. Frontiers Media S.A. 2022-03-25 /pmc/articles/PMC8990912/ /pubmed/35402525 http://dx.doi.org/10.3389/fcvm.2022.849972 Text en Copyright © 2022 Hasimbegovic, Russo, Andreas, Werner, Coti, Wiedemann, Kocher, Laufer, Hofer and Mach. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Hasimbegovic, Ena
Russo, Marco
Andreas, Martin
Werner, Paul
Coti, Iuliana
Wiedemann, Dominik
Kocher, Alfred
Laufer, Günther
Hofer, Benedikt S.
Mach, Markus
Deviations From the Ideal Plasma Volume and Isolated Tricuspid Valve Surgery—Paving the Way for New Risk Stratification Parameters
title Deviations From the Ideal Plasma Volume and Isolated Tricuspid Valve Surgery—Paving the Way for New Risk Stratification Parameters
title_full Deviations From the Ideal Plasma Volume and Isolated Tricuspid Valve Surgery—Paving the Way for New Risk Stratification Parameters
title_fullStr Deviations From the Ideal Plasma Volume and Isolated Tricuspid Valve Surgery—Paving the Way for New Risk Stratification Parameters
title_full_unstemmed Deviations From the Ideal Plasma Volume and Isolated Tricuspid Valve Surgery—Paving the Way for New Risk Stratification Parameters
title_short Deviations From the Ideal Plasma Volume and Isolated Tricuspid Valve Surgery—Paving the Way for New Risk Stratification Parameters
title_sort deviations from the ideal plasma volume and isolated tricuspid valve surgery—paving the way for new risk stratification parameters
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990912/
https://www.ncbi.nlm.nih.gov/pubmed/35402525
http://dx.doi.org/10.3389/fcvm.2022.849972
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