Genotype-Guided Prescription of Azathioprine Reduces the Incidence of Adverse Drug Reactions in TPMT Intermediate Metabolizers to a Similar Incidence as Normal Metabolizers

INTRODUCTION: Thiopurine drugs are purine nucleoside analogues used for treatment of different immune-related conditions. To date, different studies highlighted the importance of thiopurine methyltransferase (TPMT) genotyping in patients who initiate treatment with thiopurines to make an adequate do...

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Detalles Bibliográficos
Autores principales: Casajús, Ana, Zubiaur, Pablo, Méndez, Marta, Campodónico, Diana, Gómez, Antía, Navares-Gómez, Marcos, Villapalos-García, Gonzalo, Soria-Chacartegui, Paula, Novalbos, Jesús, Román, Manuel, Mejía-Abril, Gina, Ochoa, Dolores, Abad-Santos, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990928/
https://www.ncbi.nlm.nih.gov/pubmed/35192152
http://dx.doi.org/10.1007/s12325-022-02067-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990928/
https://www.ncbi.nlm.nih.gov/pubmed/35192152
http://dx.doi.org/10.1007/s12325-022-02067-8

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