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Genotype-Guided Prescription of Azathioprine Reduces the Incidence of Adverse Drug Reactions in TPMT Intermediate Metabolizers to a Similar Incidence as Normal Metabolizers
INTRODUCTION: Thiopurine drugs are purine nucleoside analogues used for treatment of different immune-related conditions. To date, different studies highlighted the importance of thiopurine methyltransferase (TPMT) genotyping in patients who initiate treatment with thiopurines to make an adequate do...
Autores principales: | Casajús, Ana, Zubiaur, Pablo, Méndez, Marta, Campodónico, Diana, Gómez, Antía, Navares-Gómez, Marcos, Villapalos-García, Gonzalo, Soria-Chacartegui, Paula, Novalbos, Jesús, Román, Manuel, Mejía-Abril, Gina, Ochoa, Dolores, Abad-Santos, Francisco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Healthcare
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990928/ https://www.ncbi.nlm.nih.gov/pubmed/35192152 http://dx.doi.org/10.1007/s12325-022-02067-8 |
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