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Prolonged exposure to simulated microgravity promotes stemness impairing morphological, metabolic and migratory profile of pancreatic cancer cells: a comprehensive proteomic, lipidomic and transcriptomic analysis
BACKGROUND: The impact of the absence of gravity on cancer cells is of great interest, especially today that space is more accessible than ever. Despite advances, few and contradictory data are available mainly due to different setup, experimental design and time point analyzed. METHODS: Exploiting...
Autores principales: | Masini, Maria Angela, Bonetto, Valentina, Manfredi, Marcello, Pastò, Anna, Barberis, Elettra, Timo, Sara, Vanella, Virginia Vita, Robotti, Elisa, Masetto, Francesca, Andreoli, Francesca, Fiore, Alessandra, Tavella, Sara, Sica, Antonio, Donadelli, Massimo, Marengo, Emilio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990939/ https://www.ncbi.nlm.nih.gov/pubmed/35391557 http://dx.doi.org/10.1007/s00018-022-04243-z |
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