Oral Trypanosoma cruzi Acute Infection in Mice Targets Primary Lymphoid Organs and Triggers Extramedullary Hematopoiesis

During the acute phase of Chagas disease, Trypanosoma cruzi circulation through the bloodstream leads to high tissue parasitism in the host. In primary lymphoid organs, progenitor cell reduction paralleled transient immunosuppression. Herein we showed that acute oral infection in mice promotes diffu...

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Detalles Bibliográficos
Autores principales: Marins-Dos-Santos, Alessandro, Ayres-Silva, Jackline de Paula, Antunes, Dina, Moreira, Carlos José de Carvalho, Pelajo-Machado, Marcelo, Alfaro, David, Zapata, Agustín G., Bonomo, Adriana Cesar, Savino, Wilson, de Meis, Juliana, Farias-de-Oliveira, Désio Aurélio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990980/
https://www.ncbi.nlm.nih.gov/pubmed/35402296
http://dx.doi.org/10.3389/fcimb.2022.800395

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