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Phase 1b study of berzosertib and cisplatin in patients with advanced triple-negative breast cancer

Platinum derivatives are commonly used for the treatment of patients with metastatic triple-negative breast cancer (TNBC). However, resistance often develops, leading to treatment failure. This expansion cohort (part C2) of the previously reported phase 1b trial (NCT02157792) is based on the recomme...

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Detalles Bibliográficos
Autores principales: Telli, Melinda L., Tolaney, Sara M., Shapiro, Geoffrey I., Middleton, Mark, Lord, Simon R., Arkenau, Hendrik Tobias, Tutt, Andrew, Abramson, Vandana, Dean, Emma, Haddad, Tufia C., Wesolowski, Robert, Ferrer-Playan, Jordi, Goddemeier, Thomas, Grombacher, Thomas, Dong, Jennifer, Fleuranceau-Morel, Patricia, Diaz-Padilla, Ivan, Plummer, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991212/
https://www.ncbi.nlm.nih.gov/pubmed/35393425
http://dx.doi.org/10.1038/s41523-022-00406-0