Some mice lacking intrinsic, as well as death receptor induced apoptosis and necroptosis, can survive to adulthood

Programmed cell death, in particular the intrinsic apoptotic pathway, has been shown to play a critical role in the shaping of tissues during embryonic development. The multi-BCL-2 Homology (BH) domain effectors of apoptosis, BAX, BAK, and BOK, are essential for cell killing in the intrinsic apoptot...

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Detalles Bibliográficos
Autores principales: Ke, Francine F. S., Brinkmann, Kerstin, Voss, Anne K., Strasser, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991225/
https://www.ncbi.nlm.nih.gov/pubmed/35393408
http://dx.doi.org/10.1038/s41419-022-04731-x

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