Primary localised bladder amyloidosis – A case report with review of the literature

Primary bladder amyloidosis, a mimicker of bladder malignancy, is a rare but important differential diagnosis for patients presenting with haematuria. We report the case of a 58-year-old man who initially presented with macroscopic haematuria and irritative urinary tract symptoms. There was no radiological evidence of a bladder mass lesion, but cystoscopy revealed an erythematous papillary lesion in the posterior bladder wall concerning for bladder malignancy. Histology demonstrated primary bladder amyloidosis, which was completely excised intraoperatively. He is undergoing regular cystoscopic surveillance and there has been no disease recurrence for 4 years since the initial diagnosis.