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Ninjurin1 drives lung tumor formation and progression by potentiating Wnt/β-Catenin signaling through Frizzled2-LRP6 assembly

BACKGROUND: Cancer stem-like cells (CSCs) play a pivotal role in lung tumor formation and progression. Nerve injury-induced protein 1 (Ninjurin1, Ninj1) has been implicated in lung cancer; however, the pathological role of Ninj1 in the context of lung tumorigenesis remains largely unknown. METHODS:...

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Detalles Bibliográficos
Autores principales:	Hyun, Seung Yeob, Min, Hye-Young, Lee, Ho Jin, Cho, Jaebeom, Boo, Hye-Jin, Noh, Myungkyung, Jang, Hyun-Ji, Lee, Hyo-Jong, Park, Choon-Sik, Park, Jong-Sook, Shin, Young Kee, Lee, Ho-Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991582/ https://www.ncbi.nlm.nih.gov/pubmed/35395804 http://dx.doi.org/10.1186/s13046-022-02323-3

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