Development and validation of polygenic risk scores for prediction of breast cancer and breast cancer subtypes in Chinese women

BACKGROUND: Studies investigating breast cancer polygenic risk score (PRS) in Chinese women are scarce. The objectives of this study were to develop and validate PRSs that could be used to stratify risk for overall and subtype-specific breast cancer in Chinese women, and to evaluate the performance...

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Detalles Bibliográficos
Autores principales: Hou, Can, Xu, Bin, Hao, Yu, Yang, Daowen, Song, Huan, Li, Jiayuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991589/
https://www.ncbi.nlm.nih.gov/pubmed/35395775
http://dx.doi.org/10.1186/s12885-022-09425-3

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