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α-Synuclein arginylation in the human brain

BACKGROUND: Alpha-synuclein (α-syn) exhibits pathological misfolding in many human neurodegenerative disorders. We previously showed that α-syn is arginylated in the mouse brain and that lack of arginylation leads to neurodegeneration in mice. METHODS: Here, we tested α-syn arginylation in human bra...

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Detalles Bibliográficos
Autores principales:	Zhao, Jun, Pan, Buyan, Fina, Marie, Huang, Yun, Shimogawa, Marie, Luk, Kelvin C., Rhoades, Elizabeth, Petersson, E. James, Dong, Dawei W., Kashina, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991655/ https://www.ncbi.nlm.nih.gov/pubmed/35395956 http://dx.doi.org/10.1186/s40035-022-00295-0

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