Immunotherapy beyond cellular therapy in follicular lymphoma: A case of complete remission after failure of two CAR‐T

Patients with relapsed follicular lymphoma who do not respond to CAR‐T have a poor outcome. We present a case of refractory follicular lymphoma who relapsed after two CAR‐T infusions and achieved a complete remission after treatment with obinutuzumab and lenalidomide. This represents a promising tre...

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Detalles Bibliográficos
Autores principales: Kase, Adam M., Kharfan‐Dabaja, Mohamed A., Donaldson, Andrew, Elliott, Jamie, Sher, Taimur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991760/
https://www.ncbi.nlm.nih.gov/pubmed/35425600
http://dx.doi.org/10.1002/ccr3.5572
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author Kase, Adam M.
Kharfan‐Dabaja, Mohamed A.
Donaldson, Andrew
Elliott, Jamie
Sher, Taimur
author_facet Kase, Adam M.
Kharfan‐Dabaja, Mohamed A.
Donaldson, Andrew
Elliott, Jamie
Sher, Taimur
author_sort Kase, Adam M.
collection PubMed
description Patients with relapsed follicular lymphoma who do not respond to CAR‐T have a poor outcome. We present a case of refractory follicular lymphoma who relapsed after two CAR‐T infusions and achieved a complete remission after treatment with obinutuzumab and lenalidomide. This represents a promising treatment option in the post‐CAR‐T setting.
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spelling pubmed-89917602022-04-13 Immunotherapy beyond cellular therapy in follicular lymphoma: A case of complete remission after failure of two CAR‐T Kase, Adam M. Kharfan‐Dabaja, Mohamed A. Donaldson, Andrew Elliott, Jamie Sher, Taimur Clin Case Rep Case Reports Patients with relapsed follicular lymphoma who do not respond to CAR‐T have a poor outcome. We present a case of refractory follicular lymphoma who relapsed after two CAR‐T infusions and achieved a complete remission after treatment with obinutuzumab and lenalidomide. This represents a promising treatment option in the post‐CAR‐T setting. John Wiley and Sons Inc. 2022-04-08 /pmc/articles/PMC8991760/ /pubmed/35425600 http://dx.doi.org/10.1002/ccr3.5572 Text en © 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Kase, Adam M.
Kharfan‐Dabaja, Mohamed A.
Donaldson, Andrew
Elliott, Jamie
Sher, Taimur
Immunotherapy beyond cellular therapy in follicular lymphoma: A case of complete remission after failure of two CAR‐T
title Immunotherapy beyond cellular therapy in follicular lymphoma: A case of complete remission after failure of two CAR‐T
title_full Immunotherapy beyond cellular therapy in follicular lymphoma: A case of complete remission after failure of two CAR‐T
title_fullStr Immunotherapy beyond cellular therapy in follicular lymphoma: A case of complete remission after failure of two CAR‐T
title_full_unstemmed Immunotherapy beyond cellular therapy in follicular lymphoma: A case of complete remission after failure of two CAR‐T
title_short Immunotherapy beyond cellular therapy in follicular lymphoma: A case of complete remission after failure of two CAR‐T
title_sort immunotherapy beyond cellular therapy in follicular lymphoma: a case of complete remission after failure of two car‐t
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991760/
https://www.ncbi.nlm.nih.gov/pubmed/35425600
http://dx.doi.org/10.1002/ccr3.5572
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