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Repurposing Probenecid for the Treatment of Heart Failure (Re-Prosper-HF): a study protocol for a randomized placebo-controlled clinical trial

BACKGROUND: Improving contractility in heart failure with reduced ejection fraction (HFrEF) has resurfaced as a potential treatment goal. Inotropic therapy is now better understood through its underlying mechanism as opposed to the observed effect of increasing contractility. Calcitropes are a subgr...

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Detalles Bibliográficos
Autores principales: Rubinstein, Jack, Robbins, Nathan, Evans, Karen, Foster, Gabrielle, Mcconeghy, Kevin, Onadeko, Toluwalope, Bunke, Julie, Parent, Melanie, Luo, Xi, Joseph, Jacob, Wu, Wen-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991789/
https://www.ncbi.nlm.nih.gov/pubmed/35392963
http://dx.doi.org/10.1186/s13063-022-06214-y