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Longitudinal profiling of circulating tumour DNA for tracking tumour dynamics in pancreatic cancer

BACKGROUND: The utility of circulating tumour DNA (ctDNA) for longitudinal tumour monitoring in pancreatic ductal adenocarcinoma (PDAC) has not been explored beyond mutations in the KRAS proto-oncogene. Here, we aimed to characterise and track patient-specific somatic ctDNA variants, to assess longi...

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Detalles Bibliográficos
Autores principales: Sivapalan, Lavanya, Thorn, Graeme J., Gadaleta, Emanuela, Kocher, Hemant M., Ross-Adams, Helen, Chelala, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991893/
https://www.ncbi.nlm.nih.gov/pubmed/35392854
http://dx.doi.org/10.1186/s12885-022-09387-6