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Safety of chronic hypertonic bicarbonate inhalation in a cigarette smoke-induced airway irritation guinea pig model

BACKGROUND: Cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD) are often associated with airway fluid acidification. Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene leads to impaired bicarbonate secretion contributing to CF airway pathology. Chroni...

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Detalles Bibliográficos
Autores principales: Csekő, Kata, Hargitai, Dóra, Draskóczi, Lilla, Kéri, Adrienn, Jaikumpun, Pongsiri, Kerémi, Beáta, Helyes, Zsuzsanna, Zsembery, Ákos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991956/
https://www.ncbi.nlm.nih.gov/pubmed/35392868
http://dx.doi.org/10.1186/s12890-022-01919-x

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