Cargando…

Shenmai injection enhances cisplatin-induced apoptosis through regulation of Mfn2-dependent mitochondrial dynamics in lung adenocarcinoma A549/DDP cells

Aim: Chemoresistance is the biggest obstacle in cancer treatment. Our previous study demonstrated that Shenmai injection (SMI), a Chinese herbal medicine, enhanced the antitumor effect of cisplatin via glucose metabolism reprogramming. This study aimed to further determine whether the SMI sensitizes...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Yushi, Sun, Ye, Zhao, Qiuyu, Liu, Chunying, Wang, Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	OAE Publishing Inc. 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992451/ https://www.ncbi.nlm.nih.gov/pubmed/35582383 http://dx.doi.org/10.20517/cdr.2021.94

Ejemplares similares

Shenmai Injection Supresses Glycolysis and Enhances Cisplatin Cytotoxicity in Cisplatin-Resistant A549/DDP Cells via the AKT-mTOR-c-Myc Signaling Pathway
por: Sun, Ye, et al.
Publicado: (2020)

Overcoming Basal Autophagy, Kangai Injection Enhances Cisplatin Cytotoxicity by Regulating FOXO3a-Dependent Autophagic Cell Death and Apoptosis in Human Lung Adenocarcinoma A549/DDP Cells
por: Zhou, Huan, et al.
Publicado: (2022)

Shenqi Fuzheng Injection Reverses Cisplatin Resistance through Mitofusin-2-Mediated Cell Cycle Arrest and Apoptosis in A549/DDP Cells
por: Xiong, Ying, et al.
Publicado: (2018)

The effect of tetrandrine combined with cisplatin on proliferation and apoptosis of A549/DDP cells and A549 cells
por: Ye, Ling-Yun, et al.
Publicado: (2017)

Cytokine-Induced Killer Cells Modulates Resistance to Cisplatin in the A549/DDP Cell Line
por: Yang, Lili, et al.
Publicado: (2017)

NMR studies of the relationship between the changes of membrane lipids and the cisplatin-resistance of A549/DDP cells
por: Huang, Zhenhua, et al.
Publicado: (2003)

An Overview of Systematic Reviews of Shenmai Injection for Healthcare
por: Lu, Ling-yan, et al.
Publicado: (2014)

Down-Regulating the Expression of miRNA-21 Inhibits the Glucose Metabolism of A549/DDP Cells and Promotes Cell Death Through the PI3K/AKT/mTOR/HIF-1α Pathway
por: Sun, Ye, et al.
Publicado: (2021)

Bu-Zhong-Yi-Qi Decoction, the Water Extract of Chinese Traditional Herbal Medicine, Enhances Cisplatin Cytotoxicity in A549/DDP Cells through Induction of Apoptosis and Autophagy
por: Yu, Ning, et al.
Publicado: (2017)

Depleted aldehyde dehydrogenase 1A1 (ALDH1A1) reverses cisplatin resistance of human lung adenocarcinoma cell A549/DDP
por: Wei, Yunyan, et al.
Publicado: (2016)

Shenmai Injection Protects Against Doxorubicin-Induced Cardiotoxicity via Maintaining Mitochondrial Homeostasis
por: Li, Lin, et al.
Publicado: (2020)

Quality monitoring of Shenmai injection by HPLC pharmacodynamic fingerprinting
por: Yang, Geng, et al.
Publicado: (2023)

Reversal effect of adenovirus-mediated human interleukin 24 transfection on the cisplatin resistance of A549/DDP lung cancer cells
por: Xu, Mingju, et al.
Publicado: (2017)

Anaphylactoid reactions induced by Shuanghuanglian injection and Shenmai injection and metabolomics analysis
por: Zhang, Chi, et al.
Publicado: (2023)

Comparative analysis of microRNA expression profiles between A549, A549/DDP and their respective exosomes
por: Qin, Xiaobing, et al.
Publicado: (2017)

Investigation of cardiovascular protective effect of Shenmai injection by network pharmacology and pharmacological evaluation
por: Li, Lin, et al.
Publicado: (2020)

Alcohol Extract of YFXJ Decoction Reverses the Drug Resistance of Human Lung Adenocarcinoma Cell Line A549/DDP
por: Liu, Zhongliang, et al.
Publicado: (2022)

Pretreatment with Shenmai Injection Protects against Coronary Microvascular Dysfunction
por: Zheng, Zhaohai, et al.
Publicado: (2022)

Effects of Shenmai injection and its bioactive components following ischemia/reperfusion in cardiomyocytes
por: YE, LI-FANG, et al.
Publicado: (2015)

Adjuvant Application of Shenmai Injection for Sepsis: A Systematic Review and Meta-Analysis
por: Sun, Ye, et al.
Publicado: (2022)

Retracted: Alcohol Extract of YFXJ Decoction Reverses the Drug Resistance of Human Lung Adenocarcinoma Cell Line A549/DDP
por: Methods in Medicine, Computational and Mathematical
Publicado: (2023)

Polyphyllin I and VII potentiate the chemosensitivity of A549/DDP cells to cisplatin by enhancing apoptosis, reversing EMT and suppressing the CIP2A/AKT/mTOR signaling axis
por: Feng, Feifei, et al.
Publicado: (2019)

Effect of Shenmai injection on preventing the development of nitroglycerin-induced tolerance in rats
por: Zhou, Qian, et al.
Publicado: (2017)

Mfn2 Affects Embryo Development via Mitochondrial Dysfunction and Apoptosis
por: Zhao, Na, et al.
Publicado: (2015)

Reversal of multidrug resistance by cisplatin-loaded magnetic Fe(3)O(4) nanoparticles in A549/DDP lung cancer cells in vitro and in vivo
por: Li, Ke, et al.
Publicado: (2013)

Knockdown of TRIM65 inhibits autophagy and cisplatin resistance in A549/DDP cells by regulating miR-138-5p/ATG7
por: Pan, Xufeng, et al.
Publicado: (2019)

Shenmai Injection Improves Energy Metabolism in Patients With Heart Failure: A Randomized Controlled Trial
por: Wang, Shao-mei, et al.
Publicado: (2020)

Shenmai injection ameliorates doxorubicin-induced myocardial injury by suppressing autophagy-apoptosis via miR-30a
por: Li, Yanyang, et al.
Publicado: (2023)

Asiatic acid re-sensitizes multidrug-resistant A549/DDP cells to cisplatin by down regulating long non-coding RNA metastasis associated lung adenocarcinoma transcript 1/β-catenin signaling
por: Cheng, Qilai, et al.
Publicado: (2022)

Treatment with 20(S)-ginsenoside Rg3 reverses multidrug resistance in A549/DDP xenograft tumors
por: Liu, Chao, et al.
Publicado: (2018)

Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
por: Chen, Hsiuchen, et al.
Publicado: (2003)

Synergistic Effect of Zuo Jin Wan on DDP-Induced Apoptosis in Human Gastric Cancer SGC-7901/DDP Cells
por: Tang, Qing-Feng, et al.
Publicado: (2014)

Tripchlorolide induces autophagy in lung cancer cells by inhibiting the PI3K/AKT/mTOR pathway and improves cisplatin sensitivity in A549/DDP cells
por: Chen, Li-Min, et al.
Publicado: (2017)

Cisplatin sensitivity and thermochemosensitisation in thermotolerant cDDP-sensitive and -resistant cell lines.
por: Hettinga, J. V., et al.
Publicado: (1995)

Liquiritin induces apoptosis and autophagy in cisplatin (DDP)-resistant gastric cancer cells in vitro and xenograft nude mice in vivo
por: Wei, Feng, et al.
Publicado: (2017)

Authentication and distinction of Shenmai injection with HPLC fingerprint analysis assisted by pattern recognition techniques
por: Lu, Xue-Feng, et al.
Publicado: (2012)

Efficacy of Shenmai injection for the treatment of chronic heart failure: A protocol of systematic review
por: Gao, Peng, et al.
Publicado: (2020)

Protective effect of Shenmai injection on doxorubicin-induced cardiotoxicity via regulation of inflammatory mediators
por: Zhang, Sheng, et al.
Publicado: (2019)

Carbohydrates and ginsenosides in shenmai injection jointly improve hematopoietic function during chemotherapy-induced myelosuppression in mice
por: Zhang, Shiyu, et al.
Publicado: (2022)

Mitochondrial Dynamics Mediated by DRP1 and MFN2 Contributes to Cisplatin Chemoresistance in Human Ovarian Cancer SKOV3 cells
por: Zou, Guang-Ping, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_t68260gr0s0k9upj5sbvksg016