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Therapeutic modulation of the CD47-SIRPα axis in the pediatric tumor microenvironment: working up an appetite

Evasion of immune surveillance is one of the hallmarks of cancer. Although the adaptive immune system has been targeted via checkpoint inhibition, many patients do not sustain durable remissions due to the heterogeneity of the tumor microenvironment, so additional strategies are needed. The innate i...

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Detalles Bibliográficos
Autores principales: Gupta, Ajay, Taslim, Cenny, Tullius, Brian P., Cripe, Timothy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992496/
https://www.ncbi.nlm.nih.gov/pubmed/35582455
http://dx.doi.org/10.20517/cdr.2020.12