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Role of circulating tumor cell spheroids in drug resistance

Cancer cell spheroids are used for drug screening as these three-dimensional (3D) assemblies recapitulate tumors more realistic than the widely employed 2D in vitro cultures. Limited drug diffusion and gradients of oxygen and nutrients in spheroids represent avascular tumor regions containing quiesc...

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Detalles Bibliográficos
Autores principales:	Hamilton, Gerhard, Rath, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	OAE Publishing Inc. 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992524/ https://www.ncbi.nlm.nih.gov/pubmed/35582592 http://dx.doi.org/10.20517/cdr.2019.47

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