Mechanisms of acquired resistance to fibroblast growth factor receptor targeted therapy

Oncogenic activation of the fibroblast growth factor receptor (FGFR) through mutations and fusions of the FGFR gene occur in a variety of different malignancies such as urothelial carcinoma and cholangiocarcinoma. Inhibition of the kinase domain of the FGFR with targeted oral FGFR inhibitors has bee...

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Detalles Bibliográficos
Autores principales: Lau, David K., Jenkins, Laura, Weickhardt, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992533/
https://www.ncbi.nlm.nih.gov/pubmed/35582593
http://dx.doi.org/10.20517/cdr.2019.42

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