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Intracrine androgen biosynthesis and drug resistance

Castration-resistant prostate cancer is the lethal form of prostate cancer and most commonly remains dependent on androgen receptor (AR) signaling. Current therapies use AR signaling inhibitors (ARSI) exemplified by abiraterone acetate, a P450c17 inhibitor, and enzalutamide, a potent AR antagonist....

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Detalles Bibliográficos
Autores principales:	Penning, Trevor M., Asangani, Irfan A., Sprenger, Cynthia, Plymate, Stephen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	OAE Publishing Inc. 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992556/ https://www.ncbi.nlm.nih.gov/pubmed/35582223 http://dx.doi.org/10.20517/cdr.2020.60

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