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Approaches to identifying drug resistance mechanisms to clinically relevant treatments in childhood rhabdomyosarcoma
Aim: Despite aggressive multiagent protocols, patients with metastatic rhabdomyosarcoma (RMS) have poor prognosis. In a recent high-risk trial (ARST0431), 25% of patients failed within the first year, while on therapy and 80% had tumor progression within 24 months. However, the mechanisms for tumor...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
OAE Publishing Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992598/ https://www.ncbi.nlm.nih.gov/pubmed/35450020 http://dx.doi.org/10.20517/cdr.2021.112 |